Watch the
MOTS-c Video
Rofé Medical staff shares their experience.
Video Transcript*
MOTS-C is amazing.
It works better in fatter, insulin-resistant people. They get that energetic fire of like all their mitochondrial turning on. If you’re a dumpster fire and you have no mitochondrial optimization and you start injecting MOTS-C, you’re like, Boooom!
Faster recovery. Felt great. More endurance. Visible results. MOTS-C is basically exercise in a bottle. Energy, performance and recovery all in one.
MOTS-C is one of my favorite peptides. It works very well with increasing your metabolism, helping with insulin resistance, overall energy and anti-aging.
This peptide is derived from your mitochondria, the part of your cells responsible for energy production. It helps regulate metabolism and improves how your body uses glucose and fat for energy.
So MOTS-C does a few things. It takes your mitochondria and increases the numbers as well as it improves the function. So what you’ll feel is you’ll feel stronger muscles, you’ll feel more energy, you’ll just feel it. And MOTS-C is one of these peptides where you take it, you feel it fairly immediately.
We started using it with patients with insulin resistance. They went from plateauing on their weight loss to then losing 5 pounds in the next couple of weeks.
We also use it for patients who have struggled with circulation issues. We had a patient just recently inform us that she had lost feeling on one of her toes. Hadn’t had feeling for years from a car accident. Started taking MOTS-C and all of a sudden she noticed when she was walking on the beach she could finally feel her toes again. And since then she’s like, I need the MOTS-C.
Tired of being tired? Ask your provider if peptide therapy is right for you.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Tired of Being Tired?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-C) is a mitochondrial-derived peptide that plays a vital role in energy metabolism, mitochondrial repair, and cellular health.* It supports efficient energy utilization, enhances physical endurance, and promotes longevity by optimizing mitochondrial function. MOTS-c is often used as part of a metabolic optimization or anti-aging protocol to help maintain energy balance and overall vitality.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Benefits of MOTS-c*
- Enhances Energy and Metabolism: Improves mitochondrial efficiency and supports cellular energy production.
- Promotes Fat Utilization: Encourages fatty acid oxidation and helps regulate glucose metabolism.
- Improves Physical Endurance: Boosts stamina and exercise recovery.
- Supports Healthy Aging: Protects against oxidative stress and age-related mitochondrial decline.
- Optimizes Metabolic Health: May improve insulin sensitivity and metabolic flexibility.
- Increases Vitality: Supports overall energy, mood, and resilience.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
About the Author
Dr. Sasson Moulavi, MD
Board-certified in family medicine with 30+ years of experience in adult medicine.
April 21, 2026
